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[The construction and expression of Saccharomyces albicans pACT1-GFP plasmids].

Authors :
Sun J
Jia F
Xia MH
Qian H
Dong H
Qi Q
Source :
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology [Hua Xi Kou Qiang Yi Xue Za Zhi] 2012 Apr; Vol. 30 (2), pp. 115-8.
Publication Year :
2012

Abstract

Objective: To construct strains containing green fluorescent protein (GFP) to study gene regulation in Saccharomyces albicans cells during the infection process.<br />Methods: pACT1-GFP was constructed, and Saccharomyces albicans CAI4 was transformed. The expression of GFP in yeast and hyphal compartments was observed with microscopy.<br />Results: 99% of Saccharomyces albicans cells containing pACT1-GFP fusion displayed significant fluorescence levels both in the yeast and hyphal compartments. The fluorescence intensity in two compartments had no obvious difference.<br />Conclusion: pACT1-GFP can be expressed stably in the yeast cells.

Details

Language :
Chinese
ISSN :
1000-1182
Volume :
30
Issue :
2
Database :
MEDLINE
Journal :
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
Publication Type :
Academic Journal
Accession number :
22594223