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[A case of disseminated carcinomatosis of bone marrow treated by S-1 and cisplatin after distal gastrectomy for early gastric cancer].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2012 May; Vol. 39 (5), pp. 813-5. - Publication Year :
- 2012
-
Abstract
- Patients with bone metastasis originating from gastric cancer experience complications from DIC. They are treated with anticoagulation therapy or platelet transfusion, but their prognosis is poor. Our case was a 50-year-old male who had undergone distal gastrectomy for early gastric cancer[pT1a(M)N0M0, pStage I a]ten years previously. He was admitted to our hospital complaining of backache. As a result of his examination, he was diagnosed with disseminated carcinosis of bone marrow with DIC as a postoperative recurrence of gastric cancer. The patient was treated with combination chemotherapy of S-1 and cisplatin(S-1 80 mg/body, po, day 1-21 and cisplatin 50mg/body, iv, day 8). After one course of treatment, DIC was resolved and his pain was relieved. He survived for about nine months. S-1 and cisplatin are considered to be effective for disseminated carcinosis of bone marrow.
- Subjects :
- Bone Marrow Neoplasms complications
Carcinoma pathology
Cisplatin administration & dosage
Disseminated Intravascular Coagulation etiology
Drug Combinations
Fatal Outcome
Gastrectomy
Humans
Male
Middle Aged
Neoplasm Staging
Oxonic Acid administration & dosage
Stomach Neoplasms pathology
Stomach Neoplasms surgery
Tegafur administration & dosage
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Bone Marrow Neoplasms drug therapy
Carcinoma drug therapy
Stomach Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 39
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 22584338