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Quinolones in perspective.
- Source :
-
The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 1990 Oct; Vol. 26 Suppl B, pp. 1-6. - Publication Year :
- 1990
-
Abstract
- Fluoroquinolones have been in use for the past five years. The agents inhibit Enterobacteriaceae, Pseudomonas aeruginosa, and staphylococci, but some agents lack activity against streptococci and none of the commercially available agents inhibits anaerobic species. The fluoroquinolones possess many pharmacological advantages which have made them excellent therapy for urinary, selected respiratory, gastrointestinal, skin, soft tissue, bone, and sexually transmitted infections. They have also proved useful as prophylaxis in neutropenic patients. A major problem for the future is that inappropriate and indiscriminate use of quinolones will cause rapid development of resistance, particularly among staphylococci and P. aeruginosa.
- Subjects :
- 4-Quinolones
Anti-Bacterial Agents
Anti-Infective Agents administration & dosage
Anti-Infective Agents pharmacokinetics
Bacteria, Anaerobic drug effects
Drug Therapy, Combination
Enterobacteriaceae Infections drug therapy
Half-Life
Humans
Pseudomonas Infections drug therapy
Staphylococcal Infections drug therapy
Streptococcus drug effects
Anti-Infective Agents therapeutic use
Bacterial Infections prevention & control
Drug Resistance, Microbial
Subjects
Details
- Language :
- English
- ISSN :
- 0305-7453
- Volume :
- 26 Suppl B
- Database :
- MEDLINE
- Journal :
- The Journal of antimicrobial chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 2258336
- Full Text :
- https://doi.org/10.1093/jac/26.suppl_b.1