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Healthy Eating, Aerobic and Resistance Training in Youth (HEARTY): study rationale, design and methods.
- Source :
-
Contemporary clinical trials [Contemp Clin Trials] 2012 Jul; Vol. 33 (4), pp. 839-47. Date of Electronic Publication: 2012 Apr 21. - Publication Year :
- 2012
-
Abstract
- Purpose: The objective of the Healthy Eating Aerobic and Resistance Training in Youth (HEARTY) trial (ClinicalTrials.Gov # NCT00195858) was to examine the effects of resistance training, with and without aerobic training, on percent body fat in sedentary, post-pubertal overweight or obese adolescents aged 14-18 years. This paper describes the HEARTY study rationale, design and methods.<br />Methods: After a 4-week supervised low-intensity exercise run-in period, 304 overweight or obese adolescents with a body mass index≥85th percentile for age and sex were randomized to 4 groups for 22 weeks (5 months): diet+aerobic exercise, diet+resistance exercise, diet+combined aerobic and resistance exercise, or a diet only waiting-list control. All participants received dietary counseling designed to promote healthy eating with a maximum daily energy deficit of -250 kcal.<br />Outcomes: The primary outcome is percent body fat measured by Magnetic Resonance Imaging. Secondary outcomes include changes in anthropometry, regional body composition, resting energy expenditure, cardiorespiratory fitness, musculoskeletal fitness, cardiometabolic risk markers, and psychological health.<br />Summary: To our knowledge, HEARTY is the largest clinical trial examining effects of aerobic training, resistance training, and combined aerobic and resistance training on changes in adiposity and cardiometabolic risk markers in overweight and obese adolescents. The findings will have important clinical implications regarding the role that resistance training should play in the management of adolescent obesity and its co-morbidities.<br /> (Copyright © 2012 Elsevier Inc. All rights reserved.)
- Subjects :
- Adiposity
Adolescent
Biomarkers blood
Body Composition
Clinical Protocols
Humans
Intention to Treat Analysis
Linear Models
Magnetic Resonance Imaging
Obesity blood
Overweight blood
Overweight therapy
Research Design
Treatment Outcome
Diet Therapy methods
Exercise
Obesity therapy
Resistance Training methods
Subjects
Details
- Language :
- English
- ISSN :
- 1559-2030
- Volume :
- 33
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Contemporary clinical trials
- Publication Type :
- Academic Journal
- Accession number :
- 22548962
- Full Text :
- https://doi.org/10.1016/j.cct.2012.04.004