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Cell type-specific eQTLs in the human immune system.
- Source :
-
Nature genetics [Nat Genet] 2012 Apr 26; Vol. 44 (5), pp. 478-80. Date of Electronic Publication: 2012 Apr 26. - Publication Year :
- 2012
-
Abstract
- A new study reports the mapping of gene expression in primary immune cell subsets, showing the presence of cell type-specific cis and trans expression quantitative trait loci (eQTLs). The identification of cell type-specific trans-regulated networks can inform functional studies of susceptibility loci identified from genome-wide association studies for human complex diseases.
Details
- Language :
- English
- ISSN :
- 1546-1718
- Volume :
- 44
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Nature genetics
- Publication Type :
- Academic Journal
- Accession number :
- 22538719
- Full Text :
- https://doi.org/10.1038/ng.2258