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A preliminary study of the T1rho values of normal knee cartilage using 3T-MRI.

Authors :
Goto H
Iwama Y
Fujii M
Aoyama N
Kubo S
Kuroda R
Ohno Y
Sugimura K
Source :
European journal of radiology [Eur J Radiol] 2012 Jul; Vol. 81 (7), pp. e796-803. Date of Electronic Publication: 2012 Apr 21.
Publication Year :
2012

Abstract

Introduction: To investigate the degree of the effect of aging and weight-bearing on T1rho values in normal cartilage.<br />Materials and Methods: Thirty-two asymptomatic patients were examined using 3.0-T magnetic resonance imaging (MRI) to determine knee cartilage T1rho values and T2 values. The femoral and tibial cartilage was divided into weight-bearing (WB-Rs) and less-weight-bearing (LWB-Rs) regions. Single regression analysis was used to assess the relationship between cartilage T1rho values and age and between T2 values and age. Analysis of variance and post hoc-testing were used to evaluate differences in WB-Rs and LWB-Rs cartilage T1rho values and T2 values. Multiple linear regression modeling was performed to predict cartilage T1rho values.<br />Results: Cartilage T1rho values correlated positively with age for all cartilage regions tested (p<0.001). There were no significant correlations between cartilage T2 values and age. In both the medial femoral and tibial cartilage, T1rho values were significantly higher in WB-Rs than in LWB-Rs (p<0.05). There were no significant differences in T2 values between WB-Rs and LWB-Rs. Multiple linear regression analysis showed that both age and weight-bearing were significant predictors of increased medial knee cartilage T1rho values (p<0.001).<br />Conclusions: Aging and the degree of weight-bearing correlate with the change in cartilage T1rho values. Based on multiple regression modeling, aging may be a more important factor than weight-bearing for cartilage T1rho values.<br /> (Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1872-7727
Volume :
81
Issue :
7
Database :
MEDLINE
Journal :
European journal of radiology
Publication Type :
Academic Journal
Accession number :
22525597
Full Text :
https://doi.org/10.1016/j.ejrad.2012.03.022