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Use of thiazolidinedione and cancer risk in Type 2 diabetes: the Hong Kong diabetes registry.
- Source :
-
Diabetes research and clinical practice [Diabetes Res Clin Pract] 2012 Jul; Vol. 97 (1), pp. e13-7. Date of Electronic Publication: 2012 Apr 11. - Publication Year :
- 2012
-
Abstract
- We examined possible anticancer effects of thiazolidinediones (TZDs) in 6074 Chinese with Type 2 diabetes free of cancer at enrolment. During a median follow-up of 4.93 years, 270 patients developed cancer. Use of TZDs was associated with reduced risk of cancer in a dose-response manner in multivariable analysis.<br /> (Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.)
- Subjects :
- Aged
Asian People
Diabetes Mellitus, Type 2 drug therapy
Dose-Response Relationship, Drug
Female
Follow-Up Studies
Hong Kong epidemiology
Humans
Hypoglycemic Agents adverse effects
Male
Metformin adverse effects
Middle Aged
Predictive Value of Tests
Registries
Thiazolidinediones pharmacology
Diabetes Mellitus, Type 2 epidemiology
Hypoglycemic Agents administration & dosage
Metformin administration & dosage
Neoplasms epidemiology
Neoplasms prevention & control
Thiazolidinediones administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1872-8227
- Volume :
- 97
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Diabetes research and clinical practice
- Publication Type :
- Academic Journal
- Accession number :
- 22502769
- Full Text :
- https://doi.org/10.1016/j.diabres.2012.03.006