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Inflammatory bowel disease in Asia: a systematic review.
- Source :
-
Journal of gastroenterology and hepatology [J Gastroenterol Hepatol] 2012 Aug; Vol. 27 (8), pp. 1266-80. - Publication Year :
- 2012
-
Abstract
- The incidence and prevalence of inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), are lower in Asia than in the West. However, across Asia the incidence and prevalence of IBD has increased rapidly over the last two to four decades. These changes may relate to increased contact with the West, westernization of diet, increasing antibiotics use, improved hygiene, vaccinations, or changes in the gut microbiota. Genetic factors also differ between Asians and the Caucasians. In Asia, UC is more prevalent than CD, although CD incidence is rapidly increasing in certain areas. There is a male predominance of CD in Asia, but a trend towards equal sex distribution for UC. IBD is diagnosed at a slightly older age than in the West, and there is rarely a second incidence peak as in the West. A positive family history is much less common than in the West, as are extra-intestinal disease manifestations. There are clear ethnic differences in incidence within countries in Asia, and an increased incidence in IBD in migrants from Asia to the West. Research in Asia, an area of rapidly changing IBD epidemiology, may lead to the discovery of critical etiologic factors that lead to the development of IBD.<br /> (© 2012 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.)
- Subjects :
- Age Factors
Asian People genetics
Colitis, Ulcerative diagnosis
Colitis, Ulcerative genetics
Colitis, Ulcerative therapy
Crohn Disease diagnosis
Crohn Disease genetics
Crohn Disease therapy
Emigrants and Immigrants statistics & numerical data
Female
Genetic Predisposition to Disease
Health Status Disparities
Humans
Incidence
Male
Prevalence
Prognosis
Risk Assessment
Risk Factors
Sex Factors
Time Factors
Asian People statistics & numerical data
Colitis, Ulcerative ethnology
Crohn Disease ethnology
Subjects
Details
- Language :
- English
- ISSN :
- 1440-1746
- Volume :
- 27
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Journal of gastroenterology and hepatology
- Publication Type :
- Academic Journal
- Accession number :
- 22497584
- Full Text :
- https://doi.org/10.1111/j.1440-1746.2012.07150.x