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Investigation on genetic heterogeneity of α-subunit of the epithelial sodium channel in rat renal cortex.

Authors :
Logvinenko NS
Herbeck YE
Ivanova LN
Source :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2011 Oct; Vol. 151 (6), pp. 709-12.
Publication Year :
2011

Abstract

Genotypic variability of αENaC mRNA in adult rat kidney caused by deletion at the 3'-end of α-subunit DNA was studied by real-time PCR using specific probes with a fluorescent dye (TaqMan). It was found that mRNA deletion forms (a and b), products of alternative splicing of aENaC gene, are absent in the cortex of adult rat kidney.

Details

Language :
English
ISSN :
1573-8221
Volume :
151
Issue :
6
Database :
MEDLINE
Journal :
Bulletin of experimental biology and medicine
Publication Type :
Academic Journal
Accession number :
22485214
Full Text :
https://doi.org/10.1007/s10517-011-1422-9