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Hepatitis B virus prevalence and vaccination response in health care workers and students at the Federal University of Bahia, Brazil.
- Source :
-
Annals of hepatology [Ann Hepatol] 2012 May-Jun; Vol. 11 (3), pp. 330-7. - Publication Year :
- 2012
-
Abstract
- Unlabelled: BACKGROUND AND RATIONALE FOR THE STUDY: Hepatitis B (HB) is one of the most prevalent occupational infections in health attendance environments. According to the Brazil Ministry of Health, health professionals must be vaccinated against the hepatitis B virus (HBV) and provide laboratory proof of immunization.<br />Aims: To evaluate the seroprevalence of HBV infection and to analyze the response to vaccine by measuring serum antibodies against HBV surface antigen (anti-HBs) levels in a sample of students and health professionals at the Federal University of Bahia.<br />Results: As part of this cross-sectional study, a campaign against occupational HB was launched in 2007 and vaccination and blood samples were collected for analysis of the following serological markers: HBV surface antigen (HBsAg) and anti-HBs (measured by enzyme-linked immunoassay) and total antibodies against HBV core antigen (anti-HBc). The study sample comprised 766 people. Global seropositivity for HBV was 1.7%: 0.5% in the students and 8.8% in the professionals. In a group of volunteers, a serological profile compatible with postvaccine immunity was shown by 95% of volunteers with proof of vaccination and by 81.8% of volunteers without proof of vaccination.<br />Conclusions: In conclusion, this study shows that it is important to promote vaccination campaigns and improve knowledge and awareness about HB among health care workers and higher education students.
- Subjects :
- Adolescent
Adult
Aged
Antibodies, Viral blood
Brazil epidemiology
Cross-Sectional Studies
Female
Hepatitis B Core Antigens immunology
Hepatitis B Surface Antigens blood
Humans
Male
Middle Aged
Occupational Exposure
Seroepidemiologic Studies
Treatment Outcome
Young Adult
Health Personnel
Hepatitis B epidemiology
Hepatitis B prevention & control
Hepatitis B Vaccines therapeutic use
Hepatitis B virus immunology
Students
Universities
Subjects
Details
- Language :
- English
- ISSN :
- 1665-2681
- Volume :
- 11
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Annals of hepatology
- Publication Type :
- Academic Journal
- Accession number :
- 22481451