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Glaucogenin E, a new C21 steroid from Cynanchum stauntonii.
- Source :
-
Natural product research [Nat Prod Res] 2013; Vol. 27 (2), pp. 176-80. Date of Electronic Publication: 2012 Apr 05. - Publication Year :
- 2013
-
Abstract
- Glaucogenin E (1), a new C(21) steroid sapogenin, along with three known ones (2-4) were isolated from the rhizomes of Cynanchum stauntonii (Decne.) Schltr. ex Levl. Their structures were established mainly by the spectroscopic analysis, including 2D NMR. All the isolated compounds were evaluated for their cytotoxicity against human cancer cell lines HeLa, Bel-7402, SGC-7901 and BGC-823.
- Subjects :
- Cell Line, Tumor
Cell Proliferation drug effects
China
Chromatography
Humans
Inhibitory Concentration 50
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Extracts isolation & purification
Plant Extracts pharmacology
Sapogenins isolation & purification
Sapogenins pharmacology
Cynanchum chemistry
Cytotoxins pharmacology
Plant Extracts analysis
Rhizome chemistry
Sapogenins analysis
Subjects
Details
- Language :
- English
- ISSN :
- 1478-6427
- Volume :
- 27
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Natural product research
- Publication Type :
- Academic Journal
- Accession number :
- 22475014
- Full Text :
- https://doi.org/10.1080/14786419.2012.665914