Back to Search
Start Over
[Extensive mesenteric ischemia related to naratriptan overuse associated with grapefruit juice absorption].
- Source :
-
Annales francaises d'anesthesie et de reanimation [Ann Fr Anesth Reanim] 2012 May; Vol. 31 (5), pp. 472-4. Date of Electronic Publication: 2012 Mar 31. - Publication Year :
- 2012
-
Abstract
- We reported the case of a 61-year-old woman, who has been hospitalized in ICU because of an extensive mesenteric ischaemia, involving the small bowel, secondary to a naratriptan overuse. This mesenteric ischaemia was complicated by multiple organ failure and was responsible for extensive small bowel resection and left colectomy. A concomitant abundant absorption of grapefruit juice, a well-known P450 inhibitor, may have enhanced this naratriptan toxicity. This case underscore that an abdominal pain occurring in the context of headache treatment may be related to a mesenteric ischaemia.<br /> (Copyright © 2012 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier SAS. All rights reserved.)
- Subjects :
- Abdominal Pain etiology
Colectomy
Electrocardiography
Female
Humans
Intestines surgery
Ischemia surgery
Middle Aged
Multiple Organ Failure complications
Shock drug therapy
Shock etiology
Citrus paradisi
Food-Drug Interactions
Ischemia chemically induced
Piperidines adverse effects
Serotonin Agents adverse effects
Splanchnic Circulation physiology
Tryptamines adverse effects
Subjects
Details
- Language :
- French
- ISSN :
- 1769-6623
- Volume :
- 31
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Annales francaises d'anesthesie et de reanimation
- Publication Type :
- Academic Journal
- Accession number :
- 22465646
- Full Text :
- https://doi.org/10.1016/j.annfar.2012.01.022