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Threefold exposure to moderate hypobaric hypoxia decreases the expression of Cu,Zn-superoxide dismutase in some regions of rat hippocampus.

Authors :
Stroev SA
Tyul'kova EI
Pelto-Huikko MT
Samoilov MO
Source :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2011 Jul; Vol. 151 (3), pp. 301-4.
Publication Year :
2011

Abstract

The effect of moderate hypobaric hypoxia on the expression of a peptide antioxidant Cu,Zn-superoxide dismutase in rat hippocampal neurons was evaluated in an immunocytochemical study. The expression of Cu,Zn-superoxide dismutase decreased significantly in the dorsal hippocampus (CA1 and CA2) and tended to decrease in ventral regions (CA3 and dentate gyrus) by the 24th hour after 3-fold exposure to hypoxia.

Details

Language :
English; Russian
ISSN :
1573-8221
Volume :
151
Issue :
3
Database :
MEDLINE
Journal :
Bulletin of experimental biology and medicine
Publication Type :
Academic Journal
Accession number :
22451871
Full Text :
https://doi.org/10.1007/s10517-011-1314-z