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Two new triterpenoid saponins from the husks of Xanthoceras sorbifolia.
- Source :
-
Natural product research [Nat Prod Res] 2013; Vol. 27 (3), pp. 232-7. Date of Electronic Publication: 2012 Mar 19. - Publication Year :
- 2013
-
Abstract
- Two new oleanane triterpenoid saponins, xanthohuskisides A (1) and B (2), were isolated from the husks of Xanthoceras sorbifolia. The structures of these two compounds were established as 3-O-β-D-glucopyranosyl (1→6)-[β-D-glucopyranosyl (1→2)]-β-D-glucopyranosyl, 28-O-β-D-glucopyranosyl (1→6)-[α-L-rhamnopyranosyl (1→2)]-β-D-glucopyranosyl 16-deoxybarringtogenol C (1) and 3-O-β-D-glucopyranosyl (1→6)-[β-D-glucopyranosyl (1→2)]-β-D-glucopyranosyl, 28-O-β-D-glucopyranosyl (1→6)-β-D-glucopyranosyl 16-deoxybarringtogenol C (2), respectively, based on the analysis on their spectral data including NMR and HR-ESI-MS. The growth inhibitory activities of compounds 1 and 2 were assayed, and 2 showed moderate activity against U937 cell line with the IG(50) value of 82.85 ± 1.58 µM.
Details
- Language :
- English
- ISSN :
- 1478-6427
- Volume :
- 27
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Natural product research
- Publication Type :
- Academic Journal
- Accession number :
- 22429027
- Full Text :
- https://doi.org/10.1080/14786419.2012.671316