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On the thermodynamics of biomolecule surface transformations.
- Source :
-
Journal of colloid and interface science [J Colloid Interface Sci] 2012 Jun 01; Vol. 375 (1), pp. 1-11. Date of Electronic Publication: 2012 Feb 24. - Publication Year :
- 2012
-
Abstract
- Biological surface science is receiving great and renewed attention owing the rising interest in applications of nanoscience and nanotechnology to biological systems, with horizons that range from nanomedicine and biomimetic photosynthesis to the unexpected effects of nanomaterials on health and environment. Biomolecule surface transformations are among the fundamental aspects of the field that remain elusive so far and urgently need to be understood to further the field. Our recent findings indicate that surface thermodynamics can give a substantial contribution toward this challenging goal. In the first part of the article, we show that biomolecule surface transformations can be framed by a general and simple thermodynamic model. Then, we explore its effectiveness by addressing some typical cases, including ligand-receptor surface binding, protein thin film machines, nanomechanical aspects of the biomolecule-nanoparticle interface and nanomechanical biosensors.<br /> (Copyright © 2012 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1095-7103
- Volume :
- 375
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of colloid and interface science
- Publication Type :
- Academic Journal
- Accession number :
- 22417912
- Full Text :
- https://doi.org/10.1016/j.jcis.2012.02.013