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Cytologic alterations in nasal mucosa after sphenopalatine artery ligation in patients with vasomotor rhinitis.
- Source :
-
American journal of rhinology & allergy [Am J Rhinol Allergy] 2012 Jan-Feb; Vol. 26 (1), pp. 49-54. - Publication Year :
- 2012
-
Abstract
- Background: Vasomotor rhinitis (VR) seems to be related to an imbalance between cholinergic and adrenergic activity in the autonomic nervous system. The nerve fibers of the sympathetic and parasympathetic nervous systems reach the nose through the posterior nasal nerve, which, after crossing the sphenopalatine foramen, distributes to the mucosa following the branches of the sphenopalatine vessels. This study was designed to evaluate the effect of sphenopalatine artery ligation on nasal function and nasal cytology in patients with VR.<br />Methods: Thirty patients with VR and bilateral inferior turbinate hypertrophy (ITH) were randomly assigned to receive endoscopic inferior turbinoplasty either with or without sphenopalatine artery ligation. Pre- (baseline) and postsurgical (1-year follow-up) assessment included fiber endoscopy, active anterior rhinomanometry, measurement of mucociliary transport time (MTt), and nasal cytology examination.<br />Results: At 1-year follow-up there was a statistically significant improvement in nasal resistances in both groups but not on intergroup comparison; MTt significantly decreased in both groups (p < 0.01) and was significantly better (p < 0.05) in the group that had undergone sphenopalatine artery ligation. Among the patients in this group, significantly fewer were found to have altered ciliated cells (p < 0.005) or a hyperchromatic supranuclear stria (p < 0.005) on nasal cytology; the differences were statistically significant also on intergroup comparison (p < 0.005 and p < 0.001, respectively).<br />Conclusion: In patients with vasomotor rhinopathy and ITH, improvement in symptoms, nasal resistance, ciliated cell trophism, and MTt was observed after sphenopalatine artery ligation.
- Subjects :
- Adult
Arteries pathology
Autonomic Fibers, Postganglionic pathology
Cilia pathology
Endoscopy
Female
Follow-Up Studies
Humans
Ligation
Male
Middle Aged
Mucociliary Clearance
Nasal Mucosa blood supply
Nasal Mucosa innervation
Nasal Mucosa surgery
Nasal Obstruction etiology
Nasal Obstruction physiopathology
Rhinitis, Vasomotor complications
Rhinitis, Vasomotor physiopathology
Treatment Outcome
Young Adult
Arteries surgery
Autonomic Fibers, Postganglionic surgery
Nasal Mucosa pathology
Nasal Obstruction pathology
Nasal Obstruction surgery
Rhinitis, Vasomotor pathology
Rhinitis, Vasomotor surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1945-8932
- Volume :
- 26
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- American journal of rhinology & allergy
- Publication Type :
- Academic Journal
- Accession number :
- 22391083
- Full Text :
- https://doi.org/10.2500/ajra.2012.26.3683