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Mediators of asthma outcomes.
- Source :
-
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2012 Mar; Vol. 129 (3 Suppl), pp. S136-41. - Publication Year :
- 2012
-
Abstract
- Background: Patient adherence, the level of asthma self-management skills, exposure to stress, and depression can have considerable influence on a wide range of asthma outcomes and thus are considered asthma outcome mediators.<br />Objective: National Institutes of Health institutes and other federal agencies convened an expert group to recommend standardized measures for 7 domains of asthma clinical research outcomes measures. Although the review of mediators of these outcomes was not within the scope of any specific outcome topic, a brief summary is presented so that researchers might consider potential mediators.<br />Methods: We prepared a summary of key mediators of asthma outcomes based on expertise and knowledge of the literature.<br />Results: The rationale for including measures of adherence, self-management skills, and exposures to stress in asthma clinical research is presented, along with a brief review of instruments for collecting this information from clinical research participants.<br />Conclusions: Appropriate measurement of adherence, self-management skills, and exposures to stress will enhance characterization of study participants and provide information about the potential impact these factors can have on mediating the effects of treatment interventions.<br /> (Published by Mosby, Inc.)
Details
- Language :
- English
- ISSN :
- 1097-6825
- Volume :
- 129
- Issue :
- 3 Suppl
- Database :
- MEDLINE
- Journal :
- The Journal of allergy and clinical immunology
- Publication Type :
- Academic Journal
- Accession number :
- 22386506
- Full Text :
- https://doi.org/10.1016/j.jaci.2011.12.987