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A rare Hb H disease due to the - -(SEA) and 16.6 kb α-thalassemia-2 deletions.

Authors :
Sroymora S
Jindadamrongwech S
Butthep P
Chuncharunee S
Source :
Hemoglobin [Hemoglobin] 2012; Vol. 36 (2), pp. 200-4. Date of Electronic Publication: 2012 Feb 29.
Publication Year :
2012

Abstract

A large deletional α-thalassemia-2 (α-thal-2) allele was identified in a Thai woman with Hb H disease. The proband has α-thal-1 (SEA type) in conjunction with a 16.6 kb deletion affecting the α2-globin allele. The proband had severe anemia and required a blood transfusion during puerperium.

Details

Language :
English
ISSN :
1532-432X
Volume :
36
Issue :
2
Database :
MEDLINE
Journal :
Hemoglobin
Publication Type :
Academic Journal
Accession number :
22376301
Full Text :
https://doi.org/10.3109/03630269.2012.655355