miR-199b-5p directly targets PODXL and DDR1 and decreased levels of miR-199b-5p correlate with elevated expressions of PODXL and DDR1 in acute myeloid leukemia.

Subjects

Subjects :

3' Untranslated Regions genetics
Bone Marrow metabolism
Bone Marrow pathology
Collagen Type IV
Discoidin Domain Receptor 1
Gene Expression Regulation, Leukemic
Gene Silencing
Genetic Vectors pharmacology
Humans
K562 Cells
Leukemia, Myeloid, Acute pathology
Leukemia, Myelomonocytic, Acute pathology
Molecular Targeted Therapy
Neoplasm Proteins biosynthesis
Receptor Protein-Tyrosine Kinases biosynthesis
Sialoglycoproteins biosynthesis
Transfection
Up-Regulation
Leukemia, Myeloid, Acute genetics
Leukemia, Myelomonocytic, Acute genetics
MicroRNAs genetics
Neoplasm Proteins genetics
Receptor Protein-Tyrosine Kinases genetics
Sialoglycoproteins genetics

Details

Language :

English

ISSN :

1096-8652

Volume :

87

Issue :

4

Database :

MEDLINE

Journal :

American journal of hematology

Publication Type :

Editorial & Opinion

Accession number :

22374871

Full Text :

https://doi.org/10.1002/ajh.23129