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Total synthesis of (+)-anamarine.

Authors :
Kumar KS
Reddy CS
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2012 Apr 07; Vol. 10 (13), pp. 2647-55. Date of Electronic Publication: 2012 Feb 22.
Publication Year :
2012

Abstract

Total synthesis of (+)-anamarine a polyoxygenated δ-pyranone natural product was accomplished via cross-metathesis protocol starting from 3-butene-1-ol and glycidol. Other key features of this synthetic strategy include use of Sharpless asymmetric epoxidation, dihydroxylation, and deoxygenation-isomerization through allene rearrangement.

Details

Language :
English
ISSN :
1477-0539
Volume :
10
Issue :
13
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
22354519
Full Text :
https://doi.org/10.1039/c2ob06940g