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Conductive hydrogels: mechanically robust hybrids for use as biomaterials.
- Source :
-
Macromolecular bioscience [Macromol Biosci] 2012 Apr; Vol. 12 (4), pp. 494-501. Date of Electronic Publication: 2012 Feb 17. - Publication Year :
- 2012
-
Abstract
- A hybrid system for producing conducting polymers within a doping hydrogel mesh is presented. These conductive hydrogels demonstrate comparable electroactivity to conventional conducting polymers without requiring the need for mobile doping ions which are typically used in literature. These hybrids have superior mechanical stability and a modulus significantly closer to neural tissue than materials which are commonly used for medical electrodes. Additionally they are shown to support the attachment and differentiation of neural like cells, with improved interaction when compared to homogeneous hydrogels. The system provides flexibility such that biologic incorporation can be tailored for application.<br /> (Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
- Subjects :
- Animals
Biocompatible Materials pharmacology
Cell Adhesion drug effects
Electric Conductivity
Electrochemical Techniques
Electrodes
Humans
Hydrogels pharmacology
Materials Testing
Methacrylates chemistry
Neurons drug effects
PC12 Cells
Photoelectron Spectroscopy
Polymerization
Rats
Tissue Engineering
Biocompatible Materials chemical synthesis
Heparin analogs & derivatives
Hydrogels chemical synthesis
Polyvinyl Alcohol chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1616-5195
- Volume :
- 12
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Macromolecular bioscience
- Publication Type :
- Academic Journal
- Accession number :
- 22344960
- Full Text :
- https://doi.org/10.1002/mabi.201100490