[Juvenile xanthogranuloma: 3 cases report and literature review].

Objective: To report the clinical characteristics and treatment of 3 patients with juvenile xanthogranuloma (JXG).
Methods: A retrospective review of the medical records of 3 patients with JXG.
Results: JXG was characterized by solitary or multiple yellowish cutaneous nodules, or eye involvement . It could also affect pituitary. JXG was easily misdiagnosed as Langerhans cell histiocytosis (LCH). Treatment for JXG was surgical excision of a solitary skin lesion and some cases might be, spontaneous regression. In cases with multisystem involvement, chemotherapy regimens used to treat LCH may be effective.
Conclusions: JXG is one of the more common non-Langerhans histiocytic proliferations and is frequently seen in infants and children. LCH-like chemotherapy is effective for patients with symptomatic multisystem JXG.