Genetic defects in PRC2 components other than EZH2 are not common in myeloid malignancies.

Authors :: Kroeze LI
Nikoloski G
da Silva-Coelho P
van Hoogen P
Stevens-Linders E
Kuiper RP
Schnittger S
Haferlach T
Pahl HL
van der Reijden BA
Jansen JH
Source :: Blood [Blood] 2012 Feb 02; Vol. 119 (5), pp. 1318-9.
Publication Year :: 2012

Subjects :: Cohort Studies
Enhancer of Zeste Homolog 2 Protein
Gene Frequency
Genetic Predisposition to Disease
Humans
Myelodysplastic Syndromes genetics
Myeloproliferative Disorders genetics
Neoplasm Proteins
Polycomb Repressive Complex 2
Polycomb-Group Proteins
Polymorphism, Single Nucleotide
Carrier Proteins genetics
DNA-Binding Proteins genetics
Genetic Variation physiology
Hematologic Neoplasms genetics
Nuclear Proteins genetics
Repressor Proteins genetics
Transcription Factors genetics

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