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A JAK-in-the-cell cycle.

Authors :
Pahl HL
Source :
Blood [Blood] 2012 Feb 02; Vol. 119 (5), pp. 1096-7.
Publication Year :
2012

Abstract

In this issue of Blood, Gautier and colleagues describe a novel signaling pathway in which deregulated JAK2 activity augments expression of a key regulator of the cell cycle, the CDC25A phosphatase, via a translational mechanism.

Details

Language :
English
ISSN :
1528-0020
Volume :
119
Issue :
5
Database :
MEDLINE
Journal :
Blood
Publication Type :
Academic Journal
Accession number :
22308276
Full Text :
https://doi.org/10.1182/blood-2011-11-393462