Writing scientific papers for publication: "Without publication research is sterile".

Background: The publication of basic science and clinical research findings, as well as new clinical diagnosis and treatment techniques, is widely disseminated. These days there is considerable competition to publish so the selection process is even more competitive.
Aim: To present advice as to how to enhance the chances of being published and more importantly how to prepare a paper for submission.
Method: Instructions are presented as to the steps to be taken in writing a scientific manuscript. This covers Introduction, Materials and Methods, Results and Discussion. Guidance is given as to what should be included and also what should be left out. The precision of writing is paramount and scientific text needs to be simple, easily read and translated by those whose day-to-day language is not English. Advice is given on journal selection and how to ensure the best chance of manuscript acceptance.