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Totally implantable central venous access ports in patients with cystic fibrosis: a multicenter prospective cohort study.
- Source :
-
The journal of vascular access [J Vasc Access] 2012 Jul-Sep; Vol. 13 (3), pp. 290-5. - Publication Year :
- 2012
-
Abstract
- Purpose: The aim of this study was to assess the incidence of late onset complications of totally implantable venous access devices (TIVAD) in patients with cystic fibrosis (CF) and to investigate possible associations between the rate of complications and different policies of TIVAD management.<br />Methods: A multicenter prospective cohort study was performed in 11 Italian CF Centers. Patients with CF and a TIVAD were recruited and followed-up.<br />Results: The study commenced on May 2008 and ended on September 2010. Eighty subjects were studied (77.5% women--mean age 27.2 years). Eighteen late complications of ports were observed (22.5%; incidence 0.96 per 1000 days of observation): three lumen occlusions, seven catheter-related infections , three port-related venous thrombosis, in addition to five other complications. A statistically significant association was found between the onset of catheter-related infection and the presence of CF-related diabetes (CFRD) (P=.0064)<br />Conclusions: Our data suggest that TIVADs represent a safe and effective device for the intermittent IV administration of drugs in people with CF. However, people with CFRD have a higher risk of developing TIVAD-related infection.
- Subjects :
- Adult
Catheter-Related Infections diagnosis
Cystic Fibrosis drug therapy
Equipment Design
Female
Humans
Incidence
Italy epidemiology
Male
Prospective Studies
Risk Assessment
Risk Factors
Time Factors
Upper Extremity Deep Vein Thrombosis diagnosis
Young Adult
Catheter Obstruction
Catheter-Related Infections epidemiology
Catheterization, Central Venous adverse effects
Catheterization, Central Venous instrumentation
Catheters, Indwelling
Central Venous Catheters
Cystic Fibrosis complications
Upper Extremity Deep Vein Thrombosis epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1724-6032
- Volume :
- 13
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The journal of vascular access
- Publication Type :
- Academic Journal
- Accession number :
- 22266592
- Full Text :
- https://doi.org/10.5301/jva.5000036