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Minocycline as potent anticonvulsant in a patient with astrocytoma and drug resistant epilepsy.
- Source :
-
Seizure [Seizure] 2012 Apr; Vol. 21 (3), pp. 227-8. Date of Electronic Publication: 2012 Jan 20. - Publication Year :
- 2012
-
Abstract
- Minocycline, a tetracycline family antibiotic, is known to inhibit microglial activation and proinflammatory cytokine release in animal models. Experimental data show that these immune processes may play a role in epilepto- and ictogenesis. We present the case of a patient with marked reduction in seizure frequency during minocycline therapy with severe symptomatic epilepsy due to an astrocytoma.<br /> (Copyright © 2011 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.)
- Subjects :
- Astrocytoma radiotherapy
Astrocytoma surgery
Brain Neoplasms radiotherapy
Brain Neoplasms surgery
Epilepsy etiology
Humans
Male
Melanoma complications
Middle Aged
Neoplasms, Multiple Primary pathology
Skin Neoplasms complications
Anticonvulsants therapeutic use
Astrocytoma complications
Brain Neoplasms complications
Epilepsy drug therapy
Minocycline therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1532-2688
- Volume :
- 21
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Seizure
- Publication Type :
- Academic Journal
- Accession number :
- 22265576
- Full Text :
- https://doi.org/10.1016/j.seizure.2011.12.009