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Age- and gender-related differences in the use of secondary medical prevention after primary vascular surgery: a nationwide follow-up study.
- Source :
-
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery [Eur J Vasc Endovasc Surg] 2012 Mar; Vol. 43 (3), pp. 300-7. Date of Electronic Publication: 2012 Jan 13. - Publication Year :
- 2012
-
Abstract
- Objective: This study examined the possible age- and gender-related differences in the use of secondary medical prevention following primary vascular reconstruction in a population-based long-term follow-up study.<br />Methods: Using information from nationwide Danish registers, we identified all patients undergoing primary vascular reconstruction in-between 1996 and 2006 (n = 20,761). Data were obtained on all filled prescriptions 6 months and 3, 5 and 10 years after primary vascular reconstruction. Comparisons were made across age and gender groups, using men 40-60 years old as a reference.<br />Results: Compared to current guidelines the overall use of secondary medical prevention was moderate to low (e.g., lipid-lowering drugs 49.5%, angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists (ACE/ATII) 43.4%, combination of lipid-lowering drugs and anti-platelet therapy and any anti-hypertensive therapy 44.7%). A decline was observed between 6 months and 3 years after surgery. Patients >80 years old were less likely to be prescribed lipid-lowering drugs and combination therapy (e.g.: adjusted risk ratio (RR) 5 years after surgery for men and women 0.63 (95% confidence interval (CI): 0.39-1.02) and 0.48 (95%CI: 0.31-0.75), respectively, whereas smaller and statistical non-significant gender-related differences were observed. The age- and gender-related differences appeared eliminated or substantially reduced in the latest part of the study period (2001-2007).<br />Conclusion: We found moderate to low use of secondary medical prevention in Denmark compared with recommendations from clinical guidelines. However, the use has increased in recent years and age- and gender-related differences have been reduced or even eliminated.<br /> (Copyright © 2011 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.)
- Subjects :
- Adult
Age Distribution
Age Factors
Aged
Aged, 80 and over
Angiotensin-Converting Enzyme Inhibitors therapeutic use
Antihypertensive Agents therapeutic use
Calcium Channel Blockers therapeutic use
Comorbidity
Denmark epidemiology
Diuretics therapeutic use
Female
Follow-Up Studies
Humans
Hypolipidemic Agents therapeutic use
Male
Middle Aged
Platelet Aggregation Inhibitors therapeutic use
Practice Guidelines as Topic
Registries
Retrospective Studies
Sex Distribution
Sex Factors
Atherosclerosis epidemiology
Atherosclerosis surgery
Peripheral Arterial Disease epidemiology
Peripheral Arterial Disease prevention & control
Secondary Prevention statistics & numerical data
Vascular Surgical Procedures statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 1532-2165
- Volume :
- 43
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 22244910
- Full Text :
- https://doi.org/10.1016/j.ejvs.2011.12.003