Back to Search
Start Over
Does the addition of cement improve the rate of local recurrence after curettage of giant cell tumours in bone?
- Source :
-
The Journal of bone and joint surgery. British volume [J Bone Joint Surg Br] 2011 Dec; Vol. 93 (12), pp. 1665-9. - Publication Year :
- 2011
-
Abstract
- We retrospectively compared the outcome after the treatment of giant cell tumours of bone either with curettage alone or with adjuvant cementation. Between 1975 and 2008, 330 patients with a giant cell tumour were treated primarily by intralesional curettage, with 84 (25%) receiving adjuvant bone cement in the cavity. The local recurrence rate for curettage alone was 29.7% (73 of 246) compared with 14.3% (12 of 84) for curettage and cementation (p = 0.001). On multivariate analysis both the stage of disease and use of cement were independent significant factors associated with local recurrence. The use of cement was associated with a higher risk of the subsequent need for joint replacement. In patients without local recurrence, 18.1% (13 of 72) of those with cement needed a subsequent joint replacement compared to 2.3% (4 of 173) of those without cement (p = 0.001). In patients who developed local recurrence, 75.0% (9 of 12) of those with previous cementation required a joint replacement, compared with 45.2% (33 of 73) of those without cement (p = 0.044).
- Subjects :
- Adolescent
Adult
Aged
Bone Neoplasms pathology
Female
Femoral Neoplasms surgery
Follow-Up Studies
Giant Cell Tumor of Bone pathology
Humans
Humerus surgery
Male
Middle Aged
Neoplasm Recurrence, Local
Radius surgery
Retrospective Studies
Tibia surgery
Treatment Outcome
Young Adult
Bone Cements therapeutic use
Bone Neoplasms surgery
Curettage
Giant Cell Tumor of Bone surgery
Orthopedic Procedures methods
Subjects
Details
- Language :
- English
- ISSN :
- 2044-5377
- Volume :
- 93
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The Journal of bone and joint surgery. British volume
- Publication Type :
- Academic Journal
- Accession number :
- 22161931
- Full Text :
- https://doi.org/10.1302/0301-620X.93B12.27663