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Monte Carlo simulation of energy-deposit clustering for ions of the same LET in liquid water.

Authors :
Francis Z
Incerti S
Ivanchenko V
Champion C
Karamitros M
Bernal MA
El Bitar Z
Source :
Physics in medicine and biology [Phys Med Biol] 2012 Jan 07; Vol. 57 (1), pp. 209-24.
Publication Year :
2012

Abstract

This work presents a Monte Carlo study of energy depositions due to protons, alpha particles and carbon ions of the same linear-energy-transfer (LET) in liquid water. The corresponding track structures were generated using the Geant4-DNA toolkit, and the energy deposition spatial distributions were analyzed using an adapted version of the DBSCAN clustering algorithm. Combining the Geant4 simulations and the clustering algorithm it was possible to compare the quality of the different radiation types. The ratios of clustered and single energy depositions are shown versus particle LET and frequency-mean lineal energies. The estimated effect of these types of radiation on biological tissues is then discussed by comparing the results obtained for different particles with the same LET.

Details

Language :
English
ISSN :
1361-6560
Volume :
57
Issue :
1
Database :
MEDLINE
Journal :
Physics in medicine and biology
Publication Type :
Academic Journal
Accession number :
22156022
Full Text :
https://doi.org/10.1088/0031-9155/57/1/209