Complicated osteoporosis in progeroid syndrome: treatment with teriparatide.

Authors :: Iglesias Bolaños P
Guijarro de Armas G
Civantos Modino S
Vega Piñero B
Pavón de Paz I
Monereo Megías S
Source :: Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry [J Clin Densitom] 2012 Jan-Mar; Vol. 15 (1), pp. 116-9. Date of Electronic Publication: 2011 Dec 09.
Publication Year :: 2012
Abstract: Human progeroid syndromes (PSs) include a group of genetic "premature aging" diseases that affect a variety of organ systems. Bone diseases are common sequelae of patients diagnosed with PSs. Teriparatide therapy is recommended for elderly men with low bone mineral density (BMD; T-score <-2.5) and at least 1 fragility fracture who are unable to tolerate bisphosphonates. We describe a 20-yr-old patient affected by PS and severe osteoporosis complicated with femoral fracture. The patient experienced a significant improvement in lumbar spine BMD after treatment with teriparatide.<br /> (Copyright © 2012 The International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.)

Subjects :: Bone Density
Humans
Male
Syndrome
Teriparatide therapeutic use
Young Adult
Bone Density Conservation Agents therapeutic use
Osteoporosis drug therapy
Osteoporosis etiology
Progeria complications

Language :: English
ISSN :: 1094-6950
Volume :: 15
Issue :: 1
Database :: MEDLINE
Journal :: Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
Publication Type :: Academic Journal
Accession number :: 22154431
Full Text :: https://doi.org/10.1016/j.jocd.2011.10.001