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Experimental infection of rabbits (Oryctolagus cuniculus) with Brucella suis biovar 1 isolated from wild hares (Lepus europaeus).
- Source :
-
Veterinary microbiology [Vet Microbiol] 2012 May 04; Vol. 156 (3-4), pp. 439-42. Date of Electronic Publication: 2011 Nov 12. - Publication Year :
- 2012
-
Abstract
- Brucella suis biovar 1 is the causative agent of brucellosis in several domestic and wild animals and it is a common agent of human brucellosis. European hares (Lepus europaeus) have been shown to be infected by B. suis biovar 1 and the transmission to other animals has been suggested. In this work, experimental rabbits (Cuniculus orictolagus) were infected with B. suis biovar 1 isolated from wild hares. Infected rabbits showed high serological response in 2 weeks after discharge and typical granulomatous lesions (2mm diameter) were found in liver, spleen and kidneys after 50 days. B. suis biovar 1 was cultured from the lesion of the organs mentioned above as well as from urine, placenta and fetuses. These data suggest that hares are a potential source for horizontal transmission of B. suis biovar 1 to other mammalians.<br /> (Copyright © 2011 Elsevier B.V. All rights reserved.)
- Subjects :
- Animals
Animals, Wild microbiology
Brucellosis pathology
Female
Kidney microbiology
Kidney pathology
Liver microbiology
Liver pathology
Male
Pregnancy
Pregnancy Complications, Infectious microbiology
Pregnancy Complications, Infectious veterinary
Spleen microbiology
Spleen pathology
Brucella suis pathogenicity
Brucellosis veterinary
Hares microbiology
Rabbits microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1873-2542
- Volume :
- 156
- Issue :
- 3-4
- Database :
- MEDLINE
- Journal :
- Veterinary microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 22137773
- Full Text :
- https://doi.org/10.1016/j.vetmic.2011.11.006