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The effects of resistance exercise and post-exercise meal timing on the iron status in iron-deficient rats.
- Source :
-
Biological trace element research [Biol Trace Elem Res] 2012 Jun; Vol. 147 (1-3), pp. 200-5. Date of Electronic Publication: 2011 Nov 30. - Publication Year :
- 2012
-
Abstract
- Resistance exercise increases heme synthesis in the bone marrow and the hemoglobin in iron-deficient rats. Post-exercise early nutrient provision facilitates skeletal muscle protein synthesis compared to late provision. However, the effects of post-exercise nutrition timing on hemoglobin synthesis are unclear. The current study investigated the effect of post-exercise meal timing on the activity of the key enzyme involved in hemoglobin synthesis, δ-aminolevulinic acid dehydratase (ALAD), in the bone marrow and examined the hemoglobin concentration in iron-deficient rats. Male 4-week-old Sprague-Dawley rats were fed an iron-deficient diet containing 12 mg iron/kg and performed climbing exercise (5 min × 6 sets/day, 3 days/week) for 3 weeks. The rats were divided into a group fed a post-exercise meal early after exercise (E) or a group fed the meal 4 h after exercise (L). A single bout of exercise performed after the 3-week training period increased the bone marrow ALAD activity, plasma iron concentration, and transferrin saturation. Although the plasma iron concentration and transferrin saturation were lower in the E group than the L group after a single bout of exercise, the basal hematocrit, hemoglobin, and TIBC after 3 weeks did not differ between the groups. Therefore, resistance exercise increases the bone marrow ALAD activity, while the post-exercise meal timing has no effect on the hemoglobin concentration in iron-deficient rats.
- Subjects :
- Animals
Bone Marrow enzymology
Bone Marrow metabolism
Diet
Hematocrit
Iron, Dietary administration & dosage
Male
Porphobilinogen Synthase blood
Porphobilinogen Synthase metabolism
Postprandial Period
Rats
Rats, Sprague-Dawley
Time Factors
Transferrin metabolism
Hemoglobins biosynthesis
Iron blood
Iron Deficiencies
Physical Conditioning, Animal physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1559-0720
- Volume :
- 147
- Issue :
- 1-3
- Database :
- MEDLINE
- Journal :
- Biological trace element research
- Publication Type :
- Academic Journal
- Accession number :
- 22127833
- Full Text :
- https://doi.org/10.1007/s12011-011-9285-5