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Malignant Brenner tumor of the ovary with transformation to trabecular carcinoid: an immunocytochemical and electron microscopic study.
- Source :
-
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists [Int J Gynecol Pathol] 2012 Jan; Vol. 31 (1), pp. 91-7. - Publication Year :
- 2012
-
Abstract
- Ovarian Brenner tumors are typically of surface epithelial-stromal origin; however, cases associated with mature cystic teratoma and/or struma ovarii possibly have a teratomatous derivation. Although argyrophil cells have been described in ovarian Brenner tumors and in urinary bladder epithelium, we are not aware of any previous reports of carcinoid arising from a malignant Brenner tumor of the ovary. In this study, we describe an 85-year-old woman who had a low-grade malignant Brenner tumor with progressive proliferation of neuroendocrine cells and transformation to trabecular carcinoid as demonstrated by immunocytochemistry and electron microscopy.
- Subjects :
- Aged, 80 and over
Brenner Tumor surgery
Brenner Tumor ultrastructure
Carcinoid Tumor ultrastructure
Cell Proliferation
Cell Transformation, Neoplastic
Diagnosis, Differential
Fatal Outcome
Female
Humans
Immunohistochemistry
Microscopy, Electron
Neuroendocrine Cells
Ovarian Neoplasms surgery
Ovarian Neoplasms ultrastructure
Struma Ovarii pathology
Brenner Tumor pathology
Carcinoid Tumor pathology
Ovarian Neoplasms pathology
Ovary pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1538-7151
- Volume :
- 31
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
- Publication Type :
- Academic Journal
- Accession number :
- 22123728
- Full Text :
- https://doi.org/10.1097/PGP.0b013e3182230e10