Grover disease (transient acantholytic dermatosis) induced by anastrozole.

We present the case of a 79-year-old woman with a history of breast cancer who developed Grover disease (transient acantholytic dermatosis) following initiation of an aromatase inhibitor, anastrozole, as adjunctive treatment of her breast cancer. A number of drugs have been associated with this condition; however, to our knowledge, this case is the first report of anastrozole-induced Grover disease.