Betaine excretion correlates with plasma homocysteine when plasma lipids are elevated.

Objectives: To reconcile observing a positive correlation of betaine excretion with homocysteine in lipid disorder patients but not other study groups.
Design and Methods: Correlations were estimated in subgroups of a control group and the lipid disorder patients.
Results: Plasma non high-density lipoprotein (non-HDL) cholesterol differed (p<0.0001) between the groups. The correlation increased with the median plasma non-HDL cholesterol in subgroups.
Conclusions: This correlation is associated with patients with elevated plasma lipids.
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