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Anti-infective surgical therapy of peri-implantitis. A 12-month prospective clinical study.
- Source :
-
Clinical oral implants research [Clin Oral Implants Res] 2012 Feb; Vol. 23 (2), pp. 205-210. Date of Electronic Publication: 2011 Aug 09. - Publication Year :
- 2012
-
Abstract
- Aim: The aim of this prospective cohort study was to evaluate an anti-infective surgical protocol for the treatment of peri-implantitis.<br />Materials and Methods: Thirty-six implants in 24 partially dentate patients with moderate to advanced peri-implantitis were treated using an anti-infective surgical protocol incorporating open flap debridement and implant surface decontamination, with adjunctive systemic amoxicillin and metronidazole. Treatment outcomes were assessed at 3, 6 and 12 months. Patient-based statistical analyses using multiple regression analyses were performed.<br />Results: There was 100% survival of treated implants at 12 months. At 3 months, there were statistically significant (P < 0.01) reductions in mean probing depths (PD), Bleeding on Probing (BoP) and suppuration. The greater the mean PD at baseline, the greater the PD reduction at 3 months. At 3 months, there was also a significant mean facial mucosal recession of 1 mm (P < 0.001). All these changes were maintained at 6 and 12 months. At 12 months, all treated implants had a mean PD < 5 mm, while 47% of the implants had complete resolution of inflammation (BoP negative). At 12 months, 92% of implants had stable crestal bone levels or bone gain. There were no significant effects of smoking on any of the treatment outcomes.<br />Conclusions: For the treatment of peri-implantitis, an anti-infective protocol incorporating surgical access, implant surface decontamination and systemic antimicrobials followed by a strict postoperative protocol was effective at 3 months with the results maintained for up to 12 months after treatment.<br /> (© 2011 John Wiley & Sons A/S.)
- Subjects :
- Amoxicillin therapeutic use
Anti-Bacterial Agents therapeutic use
Anti-Infective Agents therapeutic use
Debridement methods
Decontamination methods
Dental Prosthesis Retention
Female
Humans
Jaw, Edentulous, Partially rehabilitation
Male
Metronidazole therapeutic use
Middle Aged
Prospective Studies
Regression Analysis
Treatment Outcome
Peri-Implantitis surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1600-0501
- Volume :
- 23
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Clinical oral implants research
- Publication Type :
- Academic Journal
- Accession number :
- 22092831
- Full Text :
- https://doi.org/10.1111/j.1600-0501.2011.02276.x