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Enhancement of enantioselectivity by alcohol additives in asymmetric hydrogenation with bis(oxazolinyl)phenyl ruthenium catalysts.

Authors :
Ito J
Teshima T
Nishiyama H
Source :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2012 Jan 28; Vol. 48 (8), pp. 1105-7. Date of Electronic Publication: 2011 Nov 14.
Publication Year :
2012

Abstract

Bis(oxazolinyl)phenyl ruthenium(II) complexes were found to catalyze asymmetric hydrogenation of ketones, in which chiral bulky alcohol additives showed significant enhancement of enantioselectivity even in protic solvents.

Details

Language :
English
ISSN :
1364-548X
Volume :
48
Issue :
8
Database :
MEDLINE
Journal :
Chemical communications (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
22080393
Full Text :
https://doi.org/10.1039/c1cc16057e