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Co-morbidity of Kawasaki disease.
- Source :
-
Indian journal of pediatrics [Indian J Pediatr] 2012 Jun; Vol. 79 (6), pp. 815-7. Date of Electronic Publication: 2011 Nov 05. - Publication Year :
- 2012
-
Abstract
- Despite more than four decades of investigation, the etiology of Kawasaki disease remains obscure, and none of the proposed etiologic theories for the disease have achieved independent confirmation. Clinical and epidemiologic features support an infectious cause, but the etiology remains unclear. The authors present a case of Kawasaki disease associated with Epstein-Barr virus and Mycoplasma pneumoniae infection in a 3.5-y-old boy. He received two doses of intravenous immunoglobulin due to prolonged course of Kawasaki disease but later had complicated autoimmune haemolytic anaemia. His prolonged fever subsided after azithromycin administration. Epstein-Barr virus infection was confirmed by molecular microbiological pathology of cervical lymph node and serological tests. The serological tests for Mycoplasma pneumoniae also revealed a positive result. Thus, it is concluded that Mycoplasma pneumoniae and Epstein-Barr virus infections may occur simultaneously in a child with Kawasaki disease. In addition, autoimmune hemolytic anaemia may be noted in Kawasaki disease patients after high-dose IVIG administration. To the authors' knowledge, this is the first report of Kawasaki disease with Epstein-Barr virus and Mycoplasma pneumoniae in the English-language literature.
- Subjects :
- Anemia, Hemolytic, Autoimmune diagnosis
Child, Preschool
Epstein-Barr Virus Infections diagnosis
Humans
Male
Mucocutaneous Lymph Node Syndrome diagnosis
Pneumonia, Mycoplasma diagnosis
Anemia, Hemolytic, Autoimmune complications
Epstein-Barr Virus Infections complications
Mucocutaneous Lymph Node Syndrome complications
Pneumonia, Mycoplasma complications
Subjects
Details
- Language :
- English
- ISSN :
- 0973-7693
- Volume :
- 79
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Indian journal of pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 22057395
- Full Text :
- https://doi.org/10.1007/s12098-011-0589-4