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Protective effects of passively transferred merozoite-specific antibodies against Theileria equi in horses with severe combined immunodeficiency.
- Source :
-
Clinical and vaccine immunology : CVI [Clin Vaccine Immunol] 2012 Jan; Vol. 19 (1), pp. 100-4. Date of Electronic Publication: 2011 Oct 28. - Publication Year :
- 2012
-
Abstract
- Theileria equi immune plasma was infused into young horses (foals) with severe combined immunodeficiency. Although all foals became infected following intravenous challenge with homologous T. equi merozoite stabilate, delayed time to peak parasitemia occurred. Protective effects were associated with a predominance of passively transferred merozoite-specific IgG3.
- Subjects :
- Animals
Antibodies, Protozoan immunology
Horse Diseases therapy
Horses
Immunoglobulin G administration & dosage
Immunoglobulin G immunology
Immunologic Factors immunology
Merozoites immunology
Parasitemia prevention & control
Theileria immunology
Time Factors
Antibodies, Protozoan administration & dosage
Horse Diseases prevention & control
Immunization, Passive methods
Immunologic Factors administration & dosage
Severe Combined Immunodeficiency veterinary
Theileriasis prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1556-679X
- Volume :
- 19
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Clinical and vaccine immunology : CVI
- Publication Type :
- Academic Journal
- Accession number :
- 22038847
- Full Text :
- https://doi.org/10.1128/CVI.05301-11