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Protective effects of passively transferred merozoite-specific antibodies against Theileria equi in horses with severe combined immunodeficiency.

Authors :
Mealey RH
Kappmeyer LS
Ueti MW
Wagner B
Knowles DP
Source :
Clinical and vaccine immunology : CVI [Clin Vaccine Immunol] 2012 Jan; Vol. 19 (1), pp. 100-4. Date of Electronic Publication: 2011 Oct 28.
Publication Year :
2012

Abstract

Theileria equi immune plasma was infused into young horses (foals) with severe combined immunodeficiency. Although all foals became infected following intravenous challenge with homologous T. equi merozoite stabilate, delayed time to peak parasitemia occurred. Protective effects were associated with a predominance of passively transferred merozoite-specific IgG3.

Details

Language :
English
ISSN :
1556-679X
Volume :
19
Issue :
1
Database :
MEDLINE
Journal :
Clinical and vaccine immunology : CVI
Publication Type :
Academic Journal
Accession number :
22038847
Full Text :
https://doi.org/10.1128/CVI.05301-11