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[European guidelines for the diagnosis and management of upper urinary tract urothelial cell carcinomas: 2011 update. European Association of Urology Guideline Group for urothelial cell carcinoma of the upper urinary tract].
- Source :
-
Actas urologicas espanolas [Actas Urol Esp] 2012 Jan; Vol. 36 (1), pp. 2-14. Date of Electronic Publication: 2011 Oct 29. - Publication Year :
- 2012
-
Abstract
- Context: The European Association of Urology (EAU) Guideline Group for urothelial cell carcinoma of the upper urinary tract (UUT-UCC) has prepared new guidelines to aid clinicians in assessing the current evidence-based management of UUT-UCC and to incorporate present recommendations into daily clinical practice.<br />Objective: This paper provides a brief overview of the EAU guidelines on UUT-UCC as an aid to clinicians in their daily practice.<br />Evidence Acquisition: The recommendations provided in the current guidelines are based on a thorough review of available UUT-UCC guidelines and papers identified using a systematic search of Medline. Data on urothelial malignancies and UUT-UCCs in the literature were searched using Medline with the following keywords: urinary tract cancer, urothelial carcinomas, upper urinary tract, carcinoma, transitional cell, renal pelvis, ureter, bladder cancer, chemotherapy, nephroureterectomy, adjuvant treatment, neoadjuvant treatment, recurrence, risk factors, and survival. A panel of experts weighted the references.<br />Evidence Synthesis: There is a lack of data in the current literature to provide strong recommendations due to the rarity of the disease. A number of recent multicentre studies are now available, whereas earlier publications were based only on limited populations. However, most of these studies have been retrospective analyses. The TNM classification 2009 is recommended. Recommendations are given for diagnosis as well as for radical and conservative treatment; prognostic factors are also discussed. Recommendations are provided for patient follow-up after different therapeutic options.<br />Conclusions: These guidelines contain information for the diagnosis and treatment of individual patients according to a current standardised approach. When determining the optimal treatment regimen, physicians must take into account each individual patient's specific clinical characteristics with regard to renal function including medical comorbidities; tumour location, grade and stage; and molecular marker status.<br /> (Copyright © 2011 AEU. Published by Elsevier Espana. All rights reserved.)
- Subjects :
- BCG Vaccine administration & dosage
BCG Vaccine therapeutic use
Biomarkers, Tumor analysis
Carcinoma, Transitional Cell epidemiology
Carcinoma, Transitional Cell pathology
Chemotherapy, Adjuvant
Diagnostic Imaging methods
Evidence-Based Medicine
Humans
Kidney Neoplasms epidemiology
Kidney Neoplasms pathology
Laparoscopy
Mitomycin administration & dosage
Mitomycin therapeutic use
Neoplasm Grading
Neoplasm Invasiveness
Neoplasm Staging
Nephrectomy
Nephrostomy, Percutaneous
Prognosis
Radiotherapy, Adjuvant
Risk Factors
Ureteral Neoplasms epidemiology
Ureteral Neoplasms pathology
Ureteroscopy
Carcinoma, Transitional Cell diagnosis
Carcinoma, Transitional Cell therapy
Kidney Neoplasms diagnosis
Kidney Neoplasms therapy
Ureteral Neoplasms diagnosis
Ureteral Neoplasms therapy
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 1699-7980
- Volume :
- 36
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Actas urologicas espanolas
- Publication Type :
- Academic Journal
- Accession number :
- 22036956
- Full Text :
- https://doi.org/10.1016/j.acuro.2011.09.001