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[Causes of early mortality after liver transplantation: a twenty-years single centre experience].
- Source :
-
Annales francaises d'anesthesie et de reanimation [Ann Fr Anesth Reanim] 2011 Dec; Vol. 30 (12), pp. 899-904. Date of Electronic Publication: 2011 Oct 27. - Publication Year :
- 2011
-
Abstract
- Objective: To define the causes of mortality of patients who died within the first three months after a liver transplantation.<br />Type of Study: Retrospective, observational, and single centre study.<br />Patients and Methods: Between March 1989 and July 2010, all patients who died within three months after a liver transplantation were included. Demographic characteristics, preoperative and peroperative data, donor characteristics, postoperative complications and causes of mortality were collected.<br />Results: Among the 788 performed liver transplantations, 76 patients died in intensive care unit (11%). The main indications of liver transplantation were alcoholic cirrhosis (30%), hepatitis C (28%), hepatocarcinoma (15%), primitive or secondary biliary cirrhosis (10%). Fifty percent of the patients were categorized as Child C. The main causes of death were non-function or dysfunction with retransplantation contra-indication graft (18%), sepsis (18%), neurological complications (12%), hemorrhagic shock (13%), (9%), multiorgan failures (5%), cardiac complications (6%).<br />Conclusion: In this study, the main causes of mortality were infectious, neurological and hemorrhagic. These results emphasize the necessity for better control of sepsis, haemorrhage and immunosupressors.<br /> (Copyright © 2011 Elsevier Masson SAS. All rights reserved.)
Details
- Language :
- French
- ISSN :
- 1769-6623
- Volume :
- 30
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Annales francaises d'anesthesie et de reanimation
- Publication Type :
- Academic Journal
- Accession number :
- 22035834
- Full Text :
- https://doi.org/10.1016/j.annfar.2011.06.014