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[Correction of the immune disorders in patients with diabetes mellitus type II with complicated diabetic foot syndrome].
- Source :
-
Klinichna khirurhiia [Klin Khir] 2011 Aug (8), pp. 55-8. - Publication Year :
- 2011
-
Abstract
- There were examined 86 patients, suffering mixed form of diabetic foot syndrome. In all the patients diabetes mellitus type II was diagnosed, the disease duration have constituted (12.3 +/- 2.5) yrs at average. The immune status was estimated, using determination of the lymphocytes subpopulations with the help of the monoclonal antibodies towards antigens reaction by the flowcytometry method, as well as concentration of the main classes of immunoglobulins IgA, IgM, IgG. The investigation was performed in dynamics: immediately after a patient admittance to hospital, on the 7 - 8th, 12 - 16th and 25 - 30th day. Basing on the analysis of the data obtained, there was conclusion made, that immediately after admittance to the hospital in the patients, suffering complicated diabetic foot syndrome, the disorders of cellular immunity of degree II and of humoral immunity of I degree were revealed. The indices improvement were noted while application of certain immunocorrecting therapy.
- Subjects :
- Acetylmuramyl-Alanyl-Isoglutamine administration & dosage
Acetylmuramyl-Alanyl-Isoglutamine analogs & derivatives
Acetylmuramyl-Alanyl-Isoglutamine therapeutic use
Antigens, CD immunology
Combined Modality Therapy
Diabetes Mellitus, Type 2 complications
Diabetes Mellitus, Type 2 immunology
Diabetic Foot etiology
Diabetic Foot immunology
Drug Therapy, Combination
Flow Cytometry
Humans
Immune System Diseases immunology
Immunity, Cellular drug effects
Immunity, Humoral drug effects
Immunoglobulins blood
Immunologic Factors administration & dosage
Immunologic Factors therapeutic use
Lymphocyte Count
Middle Aged
T-Lymphocytes cytology
T-Lymphocytes drug effects
T-Lymphocytes immunology
Treatment Outcome
Diabetes Mellitus, Type 2 therapy
Diabetic Foot therapy
Immune System Diseases therapy
Subjects
Details
- Language :
- Russian
- ISSN :
- 0023-2130
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Klinichna khirurhiia
- Publication Type :
- Academic Journal
- Accession number :
- 22013692