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[Correction of the immune disorders in patients with diabetes mellitus type II with complicated diabetic foot syndrome].

Authors :
Savon IL
Source :
Klinichna khirurhiia [Klin Khir] 2011 Aug (8), pp. 55-8.
Publication Year :
2011

Abstract

There were examined 86 patients, suffering mixed form of diabetic foot syndrome. In all the patients diabetes mellitus type II was diagnosed, the disease duration have constituted (12.3 +/- 2.5) yrs at average. The immune status was estimated, using determination of the lymphocytes subpopulations with the help of the monoclonal antibodies towards antigens reaction by the flowcytometry method, as well as concentration of the main classes of immunoglobulins IgA, IgM, IgG. The investigation was performed in dynamics: immediately after a patient admittance to hospital, on the 7 - 8th, 12 - 16th and 25 - 30th day. Basing on the analysis of the data obtained, there was conclusion made, that immediately after admittance to the hospital in the patients, suffering complicated diabetic foot syndrome, the disorders of cellular immunity of degree II and of humoral immunity of I degree were revealed. The indices improvement were noted while application of certain immunocorrecting therapy.

Details

Language :
Russian
ISSN :
0023-2130
Issue :
8
Database :
MEDLINE
Journal :
Klinichna khirurhiia
Publication Type :
Academic Journal
Accession number :
22013692