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[Oxycodone and pregabalin using transdermal fentanyl patch provided relief of symptoms for postherpetic neuropathic pain in a patient with non-small cell lung cancer].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2011 Oct; Vol. 38 (10), pp. 1675-7. - Publication Year :
- 2011
-
Abstract
- This paper presents a man in his 70's with non-small cell lung cancer (cT3N2M0, Stage III A) after chemoradiation therapy during follow-up visits. He was referred to the department of palliative care 1 month after the occurrence of herpes zoster, because of pain. Opioids (transdermal fentanyl patch and rapid-release oxycodone) were administered for his cancer pain previously. Additionally, gabapentin was given for neuropathic pain uncontrolled by opioids. However, this was replaced by pregabalin because he experienced somnolence. Although numbing improved remarkably with pregabalin, the pain was only slightly improved. The dose of rapid-release oxycodone was increased and controlled-release oxycodone was added. This provided for marked pain relief. We conclude that administration of pregabalin as an analgesic adjuvant, and oxycodone, which is an opioid, should be considered in the treatment of cancer patients without improvement of neuropathic pain from herpes zoster through use of the transdermal fentanyl patch.
- Subjects :
- Aged
Analgesics, Opioid administration & dosage
Carcinoma, Non-Small-Cell Lung complications
Fentanyl administration & dosage
Fentanyl therapeutic use
Humans
Lung Neoplasms complications
Male
Neuralgia etiology
Oxycodone administration & dosage
Oxycodone therapeutic use
Palliative Care
Pregabalin
Transdermal Patch
gamma-Aminobutyric Acid administration & dosage
gamma-Aminobutyric Acid analogs & derivatives
gamma-Aminobutyric Acid therapeutic use
Analgesics, Opioid therapeutic use
Carcinoma, Non-Small-Cell Lung therapy
Lung Neoplasms therapy
Neuralgia drug therapy
Neuralgia, Postherpetic drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 38
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 21996965