Back to Search
Start Over
Beyond the serotonin hypothesis: a role for dopamine in some forms of obsessive compulsive disorder?
- Source :
-
The Journal of clinical psychiatry [J Clin Psychiatry] 1990 Aug; Vol. 51 Suppl, pp. 36-43; discussion 55-8. - Publication Year :
- 1990
-
Abstract
- It seems unlikely that a solitary disturbance in serotonin function can fully account for the pathophysiology of obsessive compulsive disorder. The authors propose that some forms of obsessive compulsive disorder, e.g., obsessive compulsive disorder with a history of Tourette's syndrome, may involve a relative or absolute derangement in both brain serotoninergic and dopaminergic systems. A role for dopamine in the pathophysiology of obsessive compulsive disorder is supported by a review of the preclinical and clinical evidence. Additional studies are needed to more directly evaluate dopamine function in patients with obsessive compulsive disorder.
Details
- Language :
- English
- ISSN :
- 0160-6689
- Volume :
- 51 Suppl
- Database :
- MEDLINE
- Journal :
- The Journal of clinical psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 2199433