Back to Search
Start Over
Copper(I) catalyzed regioselective asymmetric alkoxyamination of aryl enamide derivatives.
- Source :
-
Organic letters [Org Lett] 2011 Nov 04; Vol. 13 (21), pp. 5792-5. Date of Electronic Publication: 2011 Oct 05. - Publication Year :
- 2011
-
Abstract
- The copper(I) catalyzed reaction of an enamide with an iminoiodane, in the presence of an alcohol, triggers the direct alkoxyamination of the double bond. This transformation represents a straightforward access to α-amino aminals in a completely regio- and diastereoselective manner. Use of a chiral Box ligand allows this reaction to be carried out in an enantioselective fashion.<br /> (© 2011 American Chemical Society)
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 13
- Issue :
- 21
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 21973176
- Full Text :
- https://doi.org/10.1021/ol202367d