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Utility of the posterior to anterior mitral valve leaflets length ratio in prediction of outcome of percutaneous balloon mitral valvuloplasty.
- Source :
-
Echocardiography (Mount Kisco, N.Y.) [Echocardiography] 2011 Nov; Vol. 28 (10), pp. 1068-73. Date of Electronic Publication: 2011 Oct 04. - Publication Year :
- 2011
-
Abstract
- Background: Scoring of mitral stenosis (MS) severity is very important for selection of patients for balloon mitral valvuloplasty (BMV).<br />Objective: We propose a novel yet simple, independent parameter of MS severity based on the posterior mitral valve leaflet to anterior mitral valve leaflet length ratio (PMVL/AMVL length ratio). It could be a useful predictor to outcome of BMV.<br />Subjects and Methods: A total of 106 patients (mean age 29.1 ± 8.6 years) had MS with mitral valve score of eight or less. The length of anterior mitral valve leaflet and posterior mitral valve leaflet were measured. Patients were classified into group with ratio ≥1/2 and group of ratio <1/2. Eighty-five healthy control subjects were studied.<br />Results: Patients with PMVL/AMVL ratio ≥1/2 post-BMV had lower transmitral gradients (4.5 ± 3.1 mmHg vs. 9.7 ± 2.1 mmHg, P < 0.002) and greater mitral valve area (MVA) (2.09 ± 0.3 cm(2) vs. 1.5 ± 0.2 cm(2) , P < 0.001), lower pulmonary artery systolic pressure (PASP) (23.8 ± 14.3 mmHg vs. 34.2 ± 12.5 mmHg, P < 0.001), left atrial pressure (10.2 ± 6.7 mmHg vs. 18.9 ± 6.4 mmHg, P < 0.001), and lower incidence of de novo or worsening of mild mitral regurgitation (MR; 1.64% vs. 8.9%, 0% vs. 6.6%, P < 0.001). PMVL/AMVL length ratio was positively correlated with post-BMV MVA (r = 0.69, P < 0.002), PASP (r = 0.592, P < 0.003), and negatively correlated with incidence of de novo or worsening of mild MR (r =-0.78, -0.93, P < 0.001). The regression analyses revealed that PMVL/AMVL ratio is the best and a reliable predictor of success and outcome of BMV, hazard ratio (95% confidence interval) 0.12 (0.05-52), P < 0.001.<br />Conclusion: Length ratio of PMVL/AMVL assessment with echocardiography is an excellent simple predictor of post-BMV mitral valve area and the cardiac events.<br /> (© 2011, Wiley Periodicals, Inc.)
- Subjects :
- Adolescent
Adult
Aged
Egypt epidemiology
Female
Humans
Male
Middle Aged
Organ Size
Prevalence
Prognosis
Reproducibility of Results
Risk Assessment methods
Risk Factors
Sensitivity and Specificity
Treatment Outcome
Young Adult
Catheterization statistics & numerical data
Echocardiography methods
Echocardiography statistics & numerical data
Mitral Valve diagnostic imaging
Mitral Valve Stenosis epidemiology
Mitral Valve Stenosis therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1540-8175
- Volume :
- 28
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Echocardiography (Mount Kisco, N.Y.)
- Publication Type :
- Academic Journal
- Accession number :
- 21966895
- Full Text :
- https://doi.org/10.1111/j.1540-8175.2011.01527.x