Molecular epidemiology of Clostridium difficile strains in children compared with that of strains circulating in adults with Clostridium difficile-associated infection.

Authors :: Stoesser N
Crook DW
Fung R
Griffiths D
Harding RM
Kachrimanidou M
Keshav S
Peto TE
Vaughan A
Walker AS
Dingle KE
Source :: Journal of clinical microbiology [J Clin Microbiol] 2011 Nov; Vol. 49 (11), pp. 3994-6. Date of Electronic Publication: 2011 Sep 21.
Publication Year :: 2011
Abstract: Molecular analysis of Clostridium difficile (28 isolates) from children (n = 128) in Oxfordshire, United Kingdom, identified eight toxigenic genotypes. Six of these were isolated from 27% of concurrent adult C. difficile-associated infections studied (n = 83). No children carried hypervirulent PCR ribotype 027. Children could participate in the transmission of some adult disease-causing genotypes.

Subjects :: Adolescent
Adult
Aged
Aged, 80 and over
Child, Preschool
Clostridioides difficile genetics
DNA, Bacterial genetics
Genotype
Humans
Infant
Middle Aged
Molecular Epidemiology
Ribotyping
United Kingdom epidemiology
Young Adult
Clostridioides difficile classification
Clostridioides difficile isolation & purification
Clostridium Infections epidemiology
Clostridium Infections microbiology

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