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A double-blind, placebo-controlled trial of fluoxetine plus behavior modification in the treatment of obese binge-eaters and non-binge-eaters.
- Source :
-
The American journal of psychiatry [Am J Psychiatry] 1990 Jul; Vol. 147 (7), pp. 876-81. - Publication Year :
- 1990
-
Abstract
- To determine whether fluoxetine is effective in the long-term treatment of obesity and whether it is particularly useful in the treatment of obese binge-eaters, the authors randomly assigned 45 obese subjects (22 with binge-eating problems and 23 without binge-eating) to fluoxetine (60 mg/day) or placebo in a 52-week double-blind trial. The 21 subjects who completed the trial made 13 clinic visits and were taught basic behavior modification strategies. Patients treated with fluoxetine plus behavior modification lost significantly more weight than those treated with placebo plus behavior modification. However, the drug did not appear to have a differential benefit for binge-eaters.
- Subjects :
- Adolescent
Adult
Attitude to Health
Bulimia complications
Bulimia drug therapy
Clinical Trials as Topic
Combined Modality Therapy
Depression diagnosis
Depression psychology
Double-Blind Method
Eating drug effects
Female
Fluoxetine pharmacology
Follow-Up Studies
Humans
Male
Middle Aged
Obesity complications
Obesity drug therapy
Patient Compliance
Personality Inventory
Placebos
Weight Loss
Behavior Therapy
Bulimia therapy
Fluoxetine therapeutic use
Obesity therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0002-953X
- Volume :
- 147
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- The American journal of psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 2192563
- Full Text :
- https://doi.org/10.1176/ajp.147.7.876