Back to Search
Start Over
[Investigating the incidence of injection-site reactions associated with administration of oxaliplatin into a peripheral vein and management local adverse reactions].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2011 Sep; Vol. 38 (9), pp. 1447-52. - Publication Year :
- 2011
-
Abstract
- In Aichi Cancer Center Hospital, we investigated the incidence of injection-site reactions associated with the administration of Oxaliplatin into a peripheral vein. We evaluated the frequency and severity of symptoms, and studied ways to manage its adverse reactions from September 2009 through March 2010. Oxaliplatin was injected into a peripheral vein in more than 90% of patients, suggesting that there would be a high risk of injection-site reactions. About 60% of patients had a numeric rating score of 5 or higher in this study, and more than 60% of injection-site reactions were improved by warming the injection site. Our results suggest that warming the injection site is one effective way to manage local adverse reactions when Oxaliplatin is administered into a peripheral vein.
- Subjects :
- Adult
Aged
Aged, 80 and over
Female
Hot Temperature
Humans
Infusions, Intravenous
Male
Middle Aged
Organoplatinum Compounds administration & dosage
Organoplatinum Compounds therapeutic use
Oxaliplatin
Pain chemically induced
Veins drug effects
Colorectal Neoplasms drug therapy
Organoplatinum Compounds adverse effects
Pain prevention & control
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 38
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 21918339